Inhibitors | Comment | Organism | Structure |
---|---|---|---|
hemin | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + 4,5-dioxopentanoate | Rattus norvegicus | heme biosynthetic pathway | 5-aminolevulinate + pyruvate | - |
ir | |
L-alanine + 4,5-dioxopentanoate | Rattus norvegicus Wistar | heme biosynthetic pathway | 5-aminolevulinate + pyruvate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar | - |
Rattus norvegicus Wistar | - |
Wistar | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + 4,5-dioxopentanoate | - |
Rattus norvegicus | 5-aminolevulinate + pyruvate | - |
ir | |
L-alanine + 4,5-dioxopentanoate | heme biosynthetic pathway | Rattus norvegicus | 5-aminolevulinate + pyruvate | - |
ir | |
L-alanine + 4,5-dioxopentanoate | - |
Rattus norvegicus Wistar | 5-aminolevulinate + pyruvate | - |
ir | |
L-alanine + 4,5-dioxopentanoate | heme biosynthetic pathway | Rattus norvegicus Wistar | 5-aminolevulinate + pyruvate | - |
ir |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
30 | - |
hemin | different concentrations of alanine at fixed 4,5-dioxopentanoate concentration | Rattus norvegicus | |
42 | - |
hemin | different concentrations of 4,5-dioxopentanoate concentration at fixed alanine concentration | Rattus norvegicus |