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Literature summary for 2.6.1.39 extracted from

  • Hartline, R.A.
    Kynurenine aminotransferase from kidney supernatant (1985), Methods Enzymol., 113, 664-672.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rattus norvegicus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
2 * 45000, SDS-PAGE Rattus norvegicus
85000
-
-
Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-2-aminoadipate + 2-oxoglutarate Rattus norvegicus
-
2-oxoadipate + L-glutamate
-
r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.65
-
kynurenine aminotransferase activity Rattus norvegicus
26.1
-
alpha-aminoadipate aminotransferase activity Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,5-di-iodotyrosine + 2-oxoglutarate
-
Rattus norvegicus 3,5-diiodophenylpyruvate + L-glutamate
-
r
DL-2-aminopimelic acid + 2-oxoglutarate
-
Rattus norvegicus 2-oxoadipate + L-glutamate
-
r
L-2-aminoadipate + 2-oxoglutarate
-
Rattus norvegicus 2-oxoadipate + L-glutamate
-
r
L-norleucine + 2-oxoglutarate
-
Rattus norvegicus 2-oxohexanoate + L-glutamate
-
r
additional information less than 2% activity with L-aspartate, L-alanine, L-alpha-aminobutyrate, glycine, L-valine, L-leucine, L-isoleucine, L-norvaline, L-epsilon-aminocaproate, L-threonine, L-serine, L-homoserine, L-cysteine, L-methionine, L-lysine, L-arginine, L-citrulline, L-ornithine, L-histidine, L-tyrosine, L-tryptophan, L-phenylalanine, L-proline and L-glutamate Rattus norvegicus ?
-
?
additional information 2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 45000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
halogenated tyrosine aminotransferase
-
Rattus norvegicus

pH Stability

pH Stability pH Stability Maximum Comment Organism
6.5 7.5 apoenzyme is most stable in this range during purification Rattus norvegicus