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Literature summary for 2.6.1.36 extracted from
- Overexpression, purification and crystallization of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv (2006), Acta Crystallogr. Sect. F, F62, 572-575.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| hanging drop vapour diffusion method in 0.1 M trisodium citrate dihydrate solution containing 0.2 M ammonium acetate and 25% PEG 4000 in the pH range 5.4-6.0 | Mycobacterium tuberculosis |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | - |
SDS-PAGE | Mycobacterium tuberculosis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycobacterium tuberculosis | - |
- |
- |
| Mycobacterium tuberculosis H37Rv | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni2+-IDA column chromatography and Superdex S-200 gel filtration | Mycobacterium tuberculosis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-lysine + 2-oxoglutarate | - |
Mycobacterium tuberculosis | 2-aminoadipate 6-semialdehyde + L-glutamate | - |
r |  |
| L-lysine + 2-oxoglutarate | - |
Mycobacterium tuberculosis H37Rv | 2-aminoadipate 6-semialdehyde + L-glutamate | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | gel filtration | Mycobacterium tuberculosis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LAT | - |
Mycobacterium tuberculosis |
| lysine epsilon-aminotransferase | - |
Mycobacterium tuberculosis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Mycobacterium tuberculosis | |
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