BRENDA - Enzyme Database show
show all sequences of 2.6.1.34

Enzymic synthesis of a diamino sugar nucleotide by extracts of type XIV Diplococcus pneumoniae

Distler, J.; Kaufman, B.; Roseman, S.; Arch. Biochem. Biophys. 116, 466-478 (1966)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
additional information
not affected by EDTA
Streptococcus pneumoniae
pyridoxal 5'-phosphate
absolute requirement
Streptococcus pneumoniae
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
additional information
not affected by MgCl2 at 0.01 M
Streptococcus pneumoniae
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
Streptococcus pneumoniae
-
UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
Streptococcus pneumoniae
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Streptococcus pneumoniae
-
type XIV, ATCC 6314
-
Purification (Commentary)
Commentary
Organism
type XIV, ATCC 6314, partial
Streptococcus pneumoniae
Storage Stability
Storage Stability
Organism
-15°C, stable for at least 3 weeks
Streptococcus pneumoniae
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
-
639965
Streptococcus pneumoniae
UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
639965
Streptococcus pneumoniae
r
UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
glutamate can only partially be replaced by glutamine and cannot be replaced by asparagine and aspartate
639965
Streptococcus pneumoniae
UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
639965
Streptococcus pneumoniae
r
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Streptococcus pneumoniae
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.9
-
-
Streptococcus pneumoniae
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
additional information
not affected by EDTA
Streptococcus pneumoniae
pyridoxal 5'-phosphate
absolute requirement
Streptococcus pneumoniae
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
additional information
not affected by MgCl2 at 0.01 M
Streptococcus pneumoniae
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
Streptococcus pneumoniae
-
UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
Streptococcus pneumoniae
r
Purification (Commentary) (protein specific)
Commentary
Organism
type XIV, ATCC 6314, partial
Streptococcus pneumoniae
Storage Stability (protein specific)
Storage Stability
Organism
-15°C, stable for at least 3 weeks
Streptococcus pneumoniae
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
-
639965
Streptococcus pneumoniae
UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
639965
Streptococcus pneumoniae
r
UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
glutamate can only partially be replaced by glutamine and cannot be replaced by asparagine and aspartate
639965
Streptococcus pneumoniae
UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
639965
Streptococcus pneumoniae
r
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Streptococcus pneumoniae
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.9
-
-
Streptococcus pneumoniae
Other publictions for EC 2.6.1.34
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739604
Riegert
Structure of the external aldi ...
Campylobacter jejuni subsp. jejuni, Campylobacter jejuni subsp. jejuni ATCC 700819
Protein Sci.
24
1609-1616
2015
-
-
-
1
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
714453
Morrison
Development of a multicomponen ...
Campylobacter jejuni
Bioorg. Med. Chem.
18
8167-8171
2010
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
692984
Schoenhofen
Functional characterization of ...
Campylobacter jejuni subsp. jejuni
J. Biol. Chem.
281
723-732
2006
-
-
-
-
-
-
-
1
-
-
-
1
-
5
-
-
-
-
-
-
-
-
2
-
1
-
-
1
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
714160
Olivier
In vitro biosynthesis of UDP-N ...
Campylobacter jejuni
Biochemistry
45
13659-13669
2006
-
-
1
-
-
-
-
-
-
-
-
2
-
1
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
639965
Distler
Enzymic synthesis of a diamino ...
Streptococcus pneumoniae
Arch. Biochem. Biophys.
116
466-478
1966
2
-
-
-
-
-
-
-
-
1
-
1
-
1
-
-
1
-
-
-
-
1
2
-
1
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
1
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-