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Literature summary for 2.6.1.27 extracted from

  • Minatogawa, Y.; Noguchi, T.; Kido, R.
    Purification, characteriaztion and identification of tryptophan aminotransferase from rat brain (1976), J. Neurochem., 27, 1097-1101.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
L-glutamate inhibits activity towards tryptophan Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol also synaptosomal cytosol Rattus norvegicus 5829
-
additional information no activity in mitochondria Rattus norvegicus
-
-
synaptosome cytosol Rattus norvegicus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-hydroxytryptophan + 2-oxoglutarate
-
Rattus norvegicus 3-(5-hydroxyindole)-2-oxopropanoate + L-glutamate
-
?
5-hydroxytryptophan + oxaloacetate
-
Rattus norvegicus 3-(5-hydroxyindole)-2-oxopropanoate + L-aspartate
-
?
L-aspartate + 2-oxoglutarate
-
Rattus norvegicus oxaloacetate + L-glutamate
-
?
L-aspartate + oxaloacetate
-
Rattus norvegicus oxaloacetate + L-aspartate
-
?
L-phenylalanine + 2-oxoglutarate
-
Rattus norvegicus L-glutamate + phenylpyruvate
-
?
L-phenylalanine + oxaloacetate
-
Rattus norvegicus phenylpyruvate + L-aspartate
-
?
L-tryptophan + 2-oxoglutarate
-
Rattus norvegicus L-glutamate + 3-indole-2-oxopropanoate
-
?
L-tryptophan + oxaloacetate
-
Rattus norvegicus 3-indole-2-oxopropanoate + L-aspartate
-
?
L-tyrosine + 2-oxoglutarate
-
Rattus norvegicus L-glutamate + 3-(4-hydroxyphenyl)-2-oxopropanoate
-
?
L-tyrosine + oxaloacetate
-
Rattus norvegicus 3-(4-hydroxyphenyl)-2-oxopropanoate + L-aspartate
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
Rattus norvegicus

pI Value

Organism Comment pI Value Maximum pI Value
Rattus norvegicus
-
-
6.2