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Literature summary for 2.6.1.2 extracted from

  • McAllister, C.H.; Facette, M.; Holt, A.; Good, A.G.
    Analysis of the enzymatic properties of a broad family of alanine aminotransferases (2013), PLoS ONE, 8, e55032.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.6.1.2

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Medicago truncatula
expression in Escherichia coli Pyrococcus furiosus
expression in Escherichia coli Hordeum vulgare
expression in Escherichia coli Mus musculus
expression in Escherichia coli Saccharomyces cerevisiae
expression in Escherichia coli Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 2-oxoglutarate pH 8.0, 20°C Pyrococcus furiosus
0.02
-
 2-oxoglutarate pH 8.0, 20°C Saccharomyces cerevisiae
0.1
-
 pyruvate pH 8.0, 20°C Hordeum vulgare
0.1
-
 pyruvate pH 8.0, 20°C Arabidopsis thaliana
0.1
-
 2-oxoglutarate pH 8.0, 20°C Mus musculus
0.1
-
 2-oxoglutarate pH 8.0, 20°C Arabidopsis thaliana
0.1
-
 L-glutamate isoform AlaAT1, pH 8.0, 20°C Medicago truncatula
0.2
-
 2-oxoglutarate pH 8.0, 20°C Hordeum vulgare
0.2
-
 2-oxoglutarate isoform AlaAT1, pH 8.0, 20°C Medicago truncatula
0.3
-
 2-oxoglutarate isoform AlaAT2, pH 8.0, 20°C Medicago truncatula
0.3
-
 L-glutamate isoform AlaAT2, pH 8.0, 20°C Medicago truncatula
0.9
-
 L-glutamate pH 8.0, 20°C Pyrococcus furiosus
0.9
-
 L-glutamate pH 8.0, 20°C Saccharomyces cerevisiae
1
-
 2-oxoglutarate pH 8.0, 20°C Arabidopsis thaliana
1
-
 L-alanine isoform AlaAT1, pH 8.0, 20°C Medicago truncatula
1.5
-
 L-alanine isoform AlaAT2, pH 8.0, 20°C Medicago truncatula
2.4
-
 L-alanine pH 8.0, 20°C Arabidopsis thaliana
2.5
-
 L-glutamate pH 8.0, 20°C Arabidopsis thaliana
4
-
 L-alanine pH 8.0, 20°C Pyrococcus furiosus
4
-
 L-alanine pH 8.0, 20°C Saccharomyces cerevisiae
4.9
-
 L-glutamate pH 8.0, 20°C Hordeum vulgare
4.9
-
 L-glutamate pH 8.0, 20°C Arabidopsis thaliana
5.1
-
 pyruvate pH 8.0, 20°C Arabidopsis thaliana
5.6
-
 L-alanine pH 8.0, 20°C Hordeum vulgare
10.4
-
 L-alanine pH 8.0, 20°C Arabidopsis thaliana
12.5
-
 pyruvate pH 8.0, 20°C Mus musculus
13
-
 L-glutamate pH 8.0, 20°C Mus musculus
16.5
-
 pyruvate pH 8.0, 20°C Pyrococcus furiosus
16.5
-
 pyruvate pH 8.0, 20°C Saccharomyces cerevisiae
18
-
 pyruvate isoform AlaAT2, pH 8.0, 20°C Medicago truncatula
18.6
-
 pyruvate isoform AlaAT1, pH 8.0, 20°C Medicago truncatula
26.5
-
 L-alanine pH 8.0, 20°C Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Medicago truncatula 5737
-
cytoplasm
-
 Hordeum vulgare 5737
-
cytoplasm
-
 Arabidopsis thaliana 5737
-
mitochondrion
-
 Pyrococcus furiosus 5739
-
mitochondrion
-
 Mus musculus 5739
-
mitochondrion
-
 Saccharomyces cerevisiae 5739
-
mitochondrion
-
 Arabidopsis thaliana 5739
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana F4I7I0
-
-
Arabidopsis thaliana Q9LDV4
-
-
Hordeum vulgare P52894
-
-
Medicago truncatula
-
-
-
Mus musculus Q8QZR5
-
-
Pyrococcus furiosus Q9P9M8
-
-
Saccharomyces cerevisiae P52893
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-alanine + 2-oxoglutarate
-
 Medicago truncatula pyruvate + L-glutamate
-
 ?
L-alanine + 2-oxoglutarate
-
 Pyrococcus furiosus pyruvate + L-glutamate
-
 ?
L-alanine + 2-oxoglutarate
-
 Hordeum vulgare pyruvate + L-glutamate
-
 ?
L-alanine + 2-oxoglutarate
-
 Mus musculus pyruvate + L-glutamate
-
 ?
L-alanine + 2-oxoglutarate
-
 Saccharomyces cerevisiae pyruvate + L-glutamate
-
 ?
L-alanine + 2-oxoglutarate
-
 Arabidopsis thaliana pyruvate + L-glutamate
-
 ?
pyruvate + L-glutamate
-
 Medicago truncatula L-alanine + 2-oxoglutarate
-
 ?
pyruvate + L-glutamate
-
 Pyrococcus furiosus L-alanine + 2-oxoglutarate
-
 ?
pyruvate + L-glutamate
-
 Hordeum vulgare L-alanine + 2-oxoglutarate
-
 ?
pyruvate + L-glutamate
-
 Mus musculus L-alanine + 2-oxoglutarate
-
 ?
pyruvate + L-glutamate
-
 Saccharomyces cerevisiae L-alanine + 2-oxoglutarate
-
 ?
pyruvate + L-glutamate
-
 Arabidopsis thaliana L-alanine + 2-oxoglutarate
-
 ?

Synonyms

Synonyms Comment Organism
AlaAT1
-
 Arabidopsis thaliana
AlaAT2
-
 Arabidopsis thaliana
GPT
-
 Pyrococcus furiosus
GPT
-
 Mus musculus