Literature summary for 2.6.1.2 extracted from

Blasco, J.; Puppo, J.
Effect of heavy metals (Cu, Cd and Pb) on aspartate and alanine aminotransferase in Ruditapes philippinarum (Mollusca: Bivalvia) (1999), Comp. Biochem. Physiol. C, 122, 253-263.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Cd2+	0.2 mM, 39% inhibition of alanine aminotransferase activity measured in soft body and gills, 0.6 mM, 46% inhibition	Ruditapes philippinarum
Cu2+	inhibition of alanine aminotransferase activity in gills	Ruditapes philippinarum
Pb2+	0.7 mM, 58% inhibition of alanine aminotransferase activity measured in soft body, 0.35 mM, 32% inhibition	Ruditapes philippinarum

Organism

Organism	UniProt	Comment	Textmining
Ruditapes philippinarum	-	mollusca: bivalvia	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
digestive gland	-	Ruditapes philippinarum	-
foot	-	Ruditapes philippinarum	-
gill	-	Ruditapes philippinarum	-
soft body part	-	Ruditapes philippinarum	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-alanine + 2-oxoglutarate	-	Ruditapes philippinarum	pyruvate + L-glutamate	-	?

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Release 2023.1 (January 2023)