Literature summary for 2.6.1.2 extracted from

Richens, A.; McEwan, J.R.; Deybach, J.C.; Mumford, J.P.
Evidence for both in vivo and in vitro interaction between vigabatrin and alanine transaminase (1997), Br. J. Clin. Pharmacol., 43, 163-168.

Inhibitors

Inhibitors	Comment	Organism	Structure
vigabatrin	structural analogue to gamma-amino butyric acid, anti-epilepsy drug, 1 mM, approx. 80% inhibition in vitro, in vivo alanine aminotransferase activity is reduced 30-40% 1-2h after administration	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue	Comment	Organism	Textmining

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)