Literature summary for 2.6.1.19 extracted from

Patel, J.; Dholakiya, B.; Mishra, N.
In vitro brain GABA-transaminase activity of 1-(4-acetylphenyl)-3-aryloxypyrrolidine-2,5-dione derivatives (2013), J. Pharm. Res., 6, 442-446.

No PubMed abstract available

Search for more literature for 2.6.1.19

Inhibitors

Inhibitors	Comment	Organism	Structure
1-(4-acetylphenyl)-3-(4-bromophenyloxy)-pyrrolidine-2,5-dione	-	Mus musculus
1-(4-acetylphenyl)-3-(salicyldehydroxy)-pyrrolidine-2,5-dione	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P61922	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Mus musculus	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.1	-	pH 7.5, 37°C	Mus musculus	1-(4-acetylphenyl)-3-(4-bromophenyloxy)-pyrrolidine-2,5-dione
0.16	-	pH 7.5, 37°C	Mus musculus	1-(4-acetylphenyl)-3-(salicyldehydroxy)-pyrrolidine-2,5-dione

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Release 2023.1 (January 2023)