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Literature summary for 2.6.1.19 extracted from
- Glutamic acid decarboxylase 65, 67, and GABA-transaminase mRNA expression and total enzyme activity in the goldfish (Carassius auratus) brain (2007), Brain Res., 1147, 154-166.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carassius auratus | - |
- |
- |
| Carassius auratus | Q2PZI2 | fragment | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Carassius auratus | - |
| brain | transcripts of gamma-aminobutanoate transaminase and glutamic acid decarboxylase 65, and glutamic acid decarboxylase 67 are detected throughout the brain, largely in the ventral and medial regions of telencephalon, nucleus preopticus, nucleus recessus lateralis of the hypothalamus, and Purkinje cell layer of the cerebellum. Enzyme activity of gamma-aminobutanoate transaminase is highest in the hypothalamus and optic textum. Gamma-aminobutanoate transaminase activity is significantly higher than total glutamic acid decarboxylase activity | Carassius auratus | - |
| hypothalamus | - |
Carassius auratus | - |
| hypothalamus | enzyme activity of gamma-aminobutanoate transaminase is highest in the hypothalamus and optic textum | Carassius auratus | - |
| nucleus preopticus | transcripts of gamma-aminobutanoate transaminase and glutamic acid decarboxylase 65, and glutamic acid decarboxylase 67 are detected throughout the brain, largely in the ventral and medial regions of telencephalon, nucleus preopticus, nucleus recessus lateralis of the hypothalamus, and Purkinje cell layer of the cerebellum | Carassius auratus | - |
| nucleus recessus lateralis | transcripts of gamma-aminobutanoate transaminase and glutamic acid decarboxylase 65, and glutamic acid decarboxylase 67 are detected throughout the brain, largely in the ventral and medial regions of telencephalon, nucleus preopticus, nucleus recessus lateralis of the hypothalamus, and Purkinje cell layer of the cerebellum | Carassius auratus | - |
| optic tectum | - |
Carassius auratus | - |
| Purkinje cell | transcripts of gamma-aminobutanoate transaminase and glutamic acid decarboxylase 65, and glutamic acid decarboxylase 67 are detected throughout the brain, largely in the ventral and medial regions of telencephalon, nucleus preopticus, nucleus recessus lateralis of the hypothalamus, and Purkinje cell layer of the cerebellum | Carassius auratus | - |
| tectum mesencephali | enzyme activity of gamma-aminobutanoate transaminase is highest in the hypothalamus and optic tectum | Carassius auratus | - |
| telencephalon | transcripts of gamma-aminobutanoate transaminase and glutamic acid decarboxylase 65, and glutamic acid decarboxylase 67 are detected throughout the brain, largely in the ventral and medial regions of telencephalon, nucleus preopticus, nucleus recessus lateralis of the hypothalamus, and Purkinje cell layer of the cerebellum | Carassius auratus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-aminobutanoate + 2-oxoglutarate | - |
Carassius auratus | 4-oxobutanoate + L-glutamate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GABA transaminase | - |
Carassius auratus |
| GABA-T | - |
Carassius auratus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | 0.01 mM | Carassius auratus | |
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Release 2023.1 (January 2023)
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