Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(+/-)piperidine-3-sulfonic acid | - |
Oryctolagus cuniculus | |
2-Aminobenzenesulfonate | - |
Oryctolagus cuniculus | |
2-aminoethane phosphonic acid | - |
Oryctolagus cuniculus | |
2-N-(acetylamino)cyclohexane sulfonic acid | - |
Oryctolagus cuniculus | |
vigabatrin | - |
Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
12.8 | - |
4-aminobutanoate | at pH 8.4 and 38°C | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
3.4 units/mg in crude brain homogenate and 51.2 units/mg after 15fold purification | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-aminobutanoate + 2-oxoglutarate | - |
Oryctolagus cuniculus | 4-oxobutanoate + L-glutamate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GABA-T | - |
Oryctolagus cuniculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | 0.1 mM | Oryctolagus cuniculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.32 | - |
vigabatrin | competitive inhibition at 37°C | Oryctolagus cuniculus | |
0.364 | - |
(+/-)piperidine-3-sulfonic acid | mixed inhibition at 37°C | Oryctolagus cuniculus | |
0.434 | - |
2-Aminobenzenesulfonate | competitive inhibition at 37°C | Oryctolagus cuniculus | |
0.598 | - |
2-N-(acetylamino)cyclohexane sulfonic acid | competitive inhibition at 37°C | Oryctolagus cuniculus | |
1.01 | - |
2-aminoethane phosphonic acid | competitive inhibition at 37°C | Oryctolagus cuniculus |