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Literature summary for 2.6.1.16 extracted from
- Glutamine fructose-6-phosphate amidotransferase (GFAT) gene expression and activity in patients with type 2 diabetes: inter-relationships with hyperglycaemia and oxidative stress (2007), Clin. Biochem., 40, 952-957.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | mean glutamine:fructose 6-phosphate amidotransferase activity is significantly higher in diabetic compared to control subjects. Plasma levels of diabetic patients also exhibit increased lipid peroxidation and protein carbonylation. Glutamine:fructose 6-phosphate amidotransferase activity is positively correlated with glutamine:fructose 6-phosphate amidotransferase mRNA, HbA1c, insulin resistance, postprandial plasma glucose and levels of thiobarbituric acid reactive substances and protein carbonyl content | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
patients with type 2 diabetes | - |
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Release 2023.1 (January 2023)
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