Literature summary for 2.6.1.16 extracted from

Badet, B.; Vermoote, P.; Le Goffic, F.
Glucosamine synthetase from Escherichia coli: kinetic mechanism and inhibition by N3-fumaroyl-L-2,3-diaminopropionic derivatives (1988), Biochemistry, 27, 2282-2287.

Search for more literature for 2.6.1.16

Inhibitors

Inhibitors	Comment	Organism	Structure
6-diazo-5-oxo-L-norleucine	-	Escherichia coli
N3-(4-Methoxyfumaroyl)-L-2,3-diaminopropanoic acid	-	Escherichia coli
N3-fumaramoyl-L-2,3-diaminopropanoic acid	-	Escherichia coli
N3-fumaroyl-L-2,3-diaminopropanoic acid	-	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-glutamine + D-fructose 6-phosphate	-	Escherichia coli	L-glutamate + D-glucosamine 6-phosphate	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00035	-	N3-(4-Methoxyfumaroyl)-L-2,3-diaminopropanoic acid	pH 7.5, 37°C	Escherichia coli
0.0014	-	6-diazo-5-oxo-L-norleucine	pH 7.5, 37°C	Escherichia coli
0.0551	-	N3-fumaroyl-L-2,3-diaminopropanoic acid	pH 7.5, 37°C	Escherichia coli

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Release 2023.1 (January 2023)