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Literature summary for 2.6.1.108 extracted from

  • Miller, D.; Wang, Y.; Xu, H.; Harich, K.; White, R.H.
    Biosynthesis of the 5-(aminomethyl)-3-furanmethanol moiety of methanofuran (2014), Biochemistry, 53, 4635-4647.
    View publication on PubMed
Search for more literature for 2.6.1.108

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Methanocaldococcus jannaschii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate Methanocaldococcus jannaschii the enzyme is involved in biosynthesis of methanofuran, a coenzyme involved in the reduction of carbon dioxide to methane pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
-
 ?
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate Methanocaldococcus jannaschii DSM 2661 the enzyme is involved in biosynthesis of methanofuran, a coenzyme involved in the reduction of carbon dioxide to methane pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii Q58097
-
-
Methanocaldococcus jannaschii DSM 2661 Q58097
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Methanocaldococcus jannaschii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate
-
 Methanocaldococcus jannaschii pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
-
 ?
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate the enzyme is involved in biosynthesis of methanofuran, a coenzyme involved in the reduction of carbon dioxide to methane Methanocaldococcus jannaschii pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
-
 ?
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate
-
 Methanocaldococcus jannaschii DSM 2661 pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
-
 ?
L-alanine + 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate the enzyme is involved in biosynthesis of methanofuran, a coenzyme involved in the reduction of carbon dioxide to methane Methanocaldococcus jannaschii DSM 2661 pyruvate + 5-(aminomethyl)-3-furanmethanol phosphate
-
 ?

Synonyms

Synonyms Comment Organism
4-HFC-P:alanine aminotransferase
-
 Methanocaldococcus jannaschii
mfnC
-
 Methanocaldococcus jannaschii
MJ0684 locus name Methanocaldococcus jannaschii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
70
-
 assay at Methanocaldococcus jannaschii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Methanocaldococcus jannaschii

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate a pyridoxal 5'-phosphate protein Methanocaldococcus jannaschii

General Information

General Information Comment Organism
physiological function the enzyme is involved in biosynthesis of methanofuran, a coenzyme involved in the reduction of carbon dioxide to methane Methanocaldococcus jannaschii