Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.6.1.100 extracted from

  • Kharel, M.K.; Subba, B.; Lee, H.C.; Liou, K.; Sohng, J.K.
    Characterization of L-glutamine:2-deoxy-scyllo-inosose aminotransferase (tbmB) from Streptomyces tenebrarius (2005), Bioorg. Med. Chem. Lett., 15, 89-92.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene tbmB, expression in Escherichia coli strain BL21(DE3) Streptoalloteichus tenebrarius

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamine + 2-deoxy-scyllo-inosose Streptoalloteichus tenebrarius
-
2-oxoglutaramate + 2-deoxy-scyllo-inosamine
-
?

Organism

Organism UniProt Comment Textmining
Streptoalloteichus tenebrarius Q2MF17 gene tbmB; gene tbmB
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamine + 2-deoxy-scyllo-inosose
-
Streptoalloteichus tenebrarius 2-oxoglutaramate + 2-deoxy-scyllo-inosamine
-
?
additional information coupled assays of TbmB with BtrC and myo-inositol dehydrogenase are performed Streptoalloteichus tenebrarius ?
-
?

Synonyms

Synonyms Comment Organism
2-deoxy-scyllo-inosose aminotransferase
-
Streptoalloteichus tenebrarius
tbmB
-
Streptoalloteichus tenebrarius

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Streptoalloteichus tenebrarius

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Streptoalloteichus tenebrarius

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Streptoalloteichus tenebrarius

General Information

General Information Comment Organism
metabolism the enzyme is involved in tobramycin biosynthesis catalyzing the second step of the 2-deoxystreptamine biosynthetic pathway, 2-deoxystreptamine is a subunit of tobramycin, overview Streptoalloteichus tenebrarius