Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Digitonin | - |
Rattus norvegicus | |
Digitonin | 0.005%, 29fold activation | Rattus norvegicus | |
taurodeoxycholate | 0.005%, 1.3fold activation | Rattus norvegicus | |
Tween-80 | 0.005%, 1.4fold activation | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-O-octyl-beta-D-glucopyranoside | 0.1%, 44% inhibition | Rattus norvegicus | |
Ca2+ | 1 mM (in absence of Mn2+ or Mg2+), complete inhibition | Rattus norvegicus | |
deoxycholate | 0.01%, 70% inhibition | Rattus norvegicus | |
SDS | 0.005%, 78% inhibition | Rattus norvegicus | |
Triton X-100 | 0.05%, 53% inhibition | Rattus norvegicus | |
Zn2+ | 1 mM (in absence of Mn2+ or Mg2+), complete inhibition | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | no activity in absence of divalent metal ion, activation with 2 mM Mg2+ is 50% of that obtained with Mn2+ | Rattus norvegicus | |
Mn2+ | no activity in absence of divalent metal ion, 0.1 mM Mn2+ is required for optimal activity | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
all-trans-farnesyl diphosphate + 6 isopentenyl diphosphate | about 10% of the activity with geranyl diphosphate | Rattus norvegicus | 6 diphosphate + all-trans-nonaprenyl diphosphate | - |
? | |
geranyl diphosphate + 7 isopentenyl diphosphate | - |
Rattus norvegicus | 7 diphosphate + all-trans-nonaprenyl diphosphate | - |
? | |
geranylgeranyl diphosphate + 5 isopentenyl diphosphate | about 25% of the activity with geranyl diphosphate | Rattus norvegicus | 5 diphosphate + all-trans-nonaprenyl diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ubiquinone:trans-prenyltransferase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | 9.5 | pH 7.0: about 60% of maximal activity, pH 9.5: about 60% of maximal activity | Rattus norvegicus |