Crystallization (Comment) | Organism |
---|---|
- |
Archaeoglobus fulgidus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-phospho-L-seryl-tRNACys + sulfide | Methanococcus maripaludis | the sulfur donor for this enzyme is unknown though in vitro sulfide is sufficient. Methanococcus maripaludis encodes both the direct and indirect paths for Cys-tRNACys synthesis. While sepS (encoding SepRS) can be deleted when the organism is grown in the presence of Cys, pscS (encoding SepCysS) cannot. SepCysS may possess an additional function in Methanococcus maripaludis that is essential | L-cysteinyl-tRNACys + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Archaeoglobus fulgidus | - |
- |
- |
Archaeoglobus fulgidus | O30207 | - |
- |
Methanococcus maripaludis | - |
- |
- |
no activity in Methanobrevibacter smithii | - |
- |
- |
no activity in Methanosphaera stadtmanae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-phospho-L-seryl-tRNACys + sulfide | - |
Archaeoglobus fulgidus | L-cysteinyl-tRNACys + phosphate | - |
? | |
O-phospho-L-seryl-tRNACys + sulfide | the sulfur donor for this enzyme is unknown though in vitro sulfide is sufficient. Methanococcus maripaludis encodes both the direct and indirect paths for Cys-tRNACys synthesis. While sepS (encoding SepRS) can be deleted when the organism is grown in the presence of Cys, pscS (encoding SepCysS) cannot. SepCysS may possess an additional function in Methanococcus maripaludis that is essential | Methanococcus maripaludis | L-cysteinyl-tRNACys + phosphate | - |
? | |
O-phospho-L-seryl-tRNACys + sulfide | the sulfur donor for this enzyme is unknown though in vitro sulfide is sufficient | Archaeoglobus fulgidus | L-cysteinyl-tRNACys + phosphate | - |
? | |
O-phospho-L-seryl-tRNACys + sulfide | the sulfur donor for this enzyme is unknown though in vitro sulfide is sufficient | Methanococcus maripaludis | L-cysteinyl-tRNACys + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | x-ray crystallography | Archaeoglobus fulgidus |
Synonyms | Comment | Organism |
---|---|---|
Sep-tRNA:Cys-tRNA synthase | - |
Archaeoglobus fulgidus |
Sep-tRNA:Cys-tRNA synthase | - |
Methanococcus maripaludis |
SepCysS | - |
Archaeoglobus fulgidus |
SepCysS | - |
Methanococcus maripaludis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Archaeoglobus fulgidus | |
pyridoxal 5'-phosphate | - |
Methanococcus maripaludis | |
pyridoxal 5'-phosphate | dependent | Archaeoglobus fulgidus |