Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli Rosetta2(DE3) cells | Haemophilus influenzae |
Protein Variants | Comment | Organism |
---|---|---|
C117D | the mutant is not inhibited by fosfomycin | Haemophilus influenzae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-chloro-3-(4-methoxyphenoxy)naphthalene-1,4-dione | - |
Haemophilus influenzae | |
6-chloro-7-(4-methoxyphenoxy)quinoline-5,8-dione | - |
Haemophilus influenzae | |
7-chloro-6-(4-hydroxyphenoxy)quinoline-5,8-dione | - |
Haemophilus influenzae | |
fosfomycin | - |
Haemophilus influenzae | |
methyl 1,4-dihydroxynaphthalene-2-carboxylate | - |
Haemophilus influenzae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
46300 | - |
- |
Haemophilus influenzae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine | Haemophilus influenzae | - |
phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemophilus influenzae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA affinity column chromatography | Haemophilus influenzae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine | - |
Haemophilus influenzae | phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 46300, calculated from amino acid sequence | Haemophilus influenzae |
Synonyms | Comment | Organism |
---|---|---|
MurA | - |
Haemophilus influenzae |
UDP-N-acetylglucosamine enolpyruvyl transferase | - |
Haemophilus influenzae |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000053 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 6-chloro-7-(4-methoxyphenoxy)quinoline-5,8-dione | |
0.000064 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 7-chloro-6-(4-hydroxyphenoxy)quinoline-5,8-dione | |
0.00071 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | 2-chloro-3-(4-methoxyphenoxy)naphthalene-1,4-dione | |
0.0087 | - |
pH and temperature not specified in the publication | Haemophilus influenzae | methyl 1,4-dihydroxynaphthalene-2-carboxylate |