Literature summary for 2.5.1.66 extracted from

Gomez-Escribano, J.P.; Liras, P.; Pisabarro, A.; Martin, J.F.
An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus (2006), Mol. Microbiol., 61, 758-770.

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Protein Variants

Protein Variants	Comment	Organism
additional information	rplKDELTAPALG mutant, with an internal 12 nucleotides in-frame deletion in the rplK gene, encoding the L11 (RplK) ribosomal protein, lacking amino acids 29PALG32, shows particularly reduced expression of ceaS2 encoding carboxyethylarginine synthase	Streptomyces clavuligerus

Organism

Organism	UniProt	Comment	Textmining
Streptomyces clavuligerus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glyceraldehyde 3-phosphate + L-arginine	-	Streptomyces clavuligerus	N2-(2-carboxyethyl)-L-arginine + phosphate	-	?

Synonyms

Synonyms	Comment	Organism
carboxyethylarginine synthase	-	Streptomyces clavuligerus
CEAS	-	Streptomyces clavuligerus

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Release 2023.1 (January 2023)