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Literature summary for 2.5.1.61 extracted from

  • Juknat, A.A.; Doernemann, D.; Senger, H.
    Purification and kinetic studies on a porphobilinogen deaminase from the unicellular green alga Scenedesmus obliquus (1994), Planta, 193, 123-130.
No PubMed abstract available
Search for more literature for 2.5.1.61

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.079
-
 porphobilinogen 37°C, pH 7.4 Tetradesmus obliquus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
 gel filtration Tetradesmus obliquus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
porphobilinogen Tetradesmus obliquus
-
 ?
-
 ?
porphobilinogen Escherichia coli
-
 ?
-
 ?
porphobilinogen Homo sapiens
-
 ?
-
 ?
porphobilinogen Rattus norvegicus
-
 ?
-
 ?
porphobilinogen Saccharomyces cerevisiae
-
 ?
-
 ?
porphobilinogen Euglena gracilis
-
 ?
-
 ?
porphobilinogen Cereibacter sphaeroides
-
 ?
-
 ?
porphobilinogen Spinacia oleracea
-
 ?
-
 ?
porphobilinogen Pisum sativum
-
 ?
-
 ?
porphobilinogen Chlorella regularis
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cereibacter sphaeroides
-
-
-
Chlorella regularis
-
-
-
Escherichia coli
-
-
-
Euglena gracilis
-
-
-
Homo sapiens
-
-
-
Pisum sativum
-
 pea
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-
Spinacia oleracea
-
 spinach
-
Tetradesmus obliquus
-
 wild-type D3, Sammlung von Algenkulturen, Pflanzenphysiologisches Institiut Universit„t G”ttingen, Germany
-

Purification (Commentary)

Purification (Comment) Organism
-
 Tetradesmus obliquus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.113
-
 at pH 7.4 Tetradesmus obliquus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Tetradesmus obliquus uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Escherichia coli uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Homo sapiens uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Rattus norvegicus uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Saccharomyces cerevisiae uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Euglena gracilis uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Cereibacter sphaeroides uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Spinacia oleracea uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Pisum sativum uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Chlorella regularis uroporphyrinogen III + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Tetradesmus obliquus hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Escherichia coli hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Homo sapiens hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Rattus norvegicus hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Saccharomyces cerevisiae hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Euglena gracilis hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Cereibacter sphaeroides hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Spinacia oleracea hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Pisum sativum hydroxylmethylbilane + 4 NH3
-
 ?
4 porphobilinogen + H2O
-
 Chlorella regularis hydroxylmethylbilane + 4 NH3
-
 ?
porphobilinogen
-
 Tetradesmus obliquus ?
-
 ?
porphobilinogen
-
 Escherichia coli ?
-
 ?
porphobilinogen
-
 Homo sapiens ?
-
 ?
porphobilinogen
-
 Rattus norvegicus ?
-
 ?
porphobilinogen
-
 Saccharomyces cerevisiae ?
-
 ?
porphobilinogen
-
 Euglena gracilis ?
-
 ?
porphobilinogen
-
 Cereibacter sphaeroides ?
-
 ?
porphobilinogen
-
 Spinacia oleracea ?
-
 ?
porphobilinogen
-
 Pisum sativum ?
-
 ?
porphobilinogen
-
 Chlorella regularis ?
-
 ?

Synonyms

Synonyms Comment Organism
PBG-D
-
 Tetradesmus obliquus
PBG-D
-
 Rattus norvegicus
PBG-D
-
 Saccharomyces cerevisiae
porphobilinogen deaminase
-
 Tetradesmus obliquus
porphobilinogen deaminase
-
 Escherichia coli
porphobilinogen deaminase
-
 Homo sapiens
porphobilinogen deaminase
-
 Rattus norvegicus
porphobilinogen deaminase
-
 Euglena gracilis
porphobilinogen deaminase
-
 Cereibacter sphaeroides
porphobilinogen deaminase
-
 Pisum sativum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
-
 Tetradesmus obliquus
additional information
-
-
 Homo sapiens
6.9
-
-
 Tetradesmus obliquus

pH Range

pH Minimum pH Maximum Comment Organism
additional information
-
-
 Tetradesmus obliquus
additional information
-
-
 Escherichia coli
additional information
-
-
 Euglena gracilis
6.3 7.5 pH 6.3 and pH 7.5: 85% of maximal activity Tetradesmus obliquus