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Literature summary for 2.5.1.61 extracted from

  • Corrigall, A.V.; Meissner, P.N.; Kirsch, R.E.
    Purification of human erythrocyte porphobilinogen deaminase (1991), S. Afr. Med. J., 80, 294-269.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0089
-
porphobilinogen
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41000
-
1 * 41000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens third enzyme in the heme biosynthetic pathway ?
-
?
porphobilinogen Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
lymphoblast
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0402
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Homo sapiens uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen + H2O
-
Homo sapiens hydroxylmethylbilane + 4 NH3
-
?
additional information third enzyme in the heme biosynthetic pathway Homo sapiens ?
-
?
porphobilinogen
-
Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
monomer 1 * 41000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
PBG-deaminase
-
Homo sapiens
porphobilinogen deaminase
-
Homo sapiens