Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-methionine + H2O | Schizosaccharomyces pombe | - |
phosphate + diphosphate + S-adenosyl-L-methionine | - |
? | |
ATP + L-methionine + H2O | Schizosaccharomyces pombe ATCC 24843 | - |
phosphate + diphosphate + S-adenosyl-L-methionine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schizosaccharomyces pombe | O60198 | - |
- |
Schizosaccharomyces pombe ATCC 24843 | O60198 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-methionine + H2O | - |
Schizosaccharomyces pombe | phosphate + diphosphate + S-adenosyl-L-methionine | - |
? | |
ATP + L-methionine + H2O | - |
Schizosaccharomyces pombe ATCC 24843 | phosphate + diphosphate + S-adenosyl-L-methionine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
S-adenosylmethionine synthetase | - |
Schizosaccharomyces pombe |
Sam1 | - |
Schizosaccharomyces pombe |
General Information | Comment | Organism |
---|---|---|
malfunction | sam1 mutants lose viability during nitrogen starvation-induced G0 phase quiescence. After release from the G0 state, sam1 mutants could neither increase in cell size nor re-initiate DNA replication in the rich medium | Schizosaccharomyces pombe |
metabolism | the product S-adenosylmethionine serves as the methyl donor in most methyl transfer reactions, including methylation of proteins, nucleic acids, and lipids. The enzyme is required for cell growth and proliferation, and maintenance of and exit from quiescence | Schizosaccharomyces pombe |