Literature summary for 2.5.1.6 extracted from

Tabuchi, T.; Kawaguchi, Y.; Azuma, T.; Nanmori, T.; Yasuda, T.
Similar regulation patterns of choline monooxygenase, phosphoethanolamine N-methyltransferase and S-adenosyl-L-methionine synthetase in leaves of the halophyte Atriplex nummularia L (2005), Plant Cell Physiol., 46, 505-513.

Search for more literature for 2.5.1.6

Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	salt stress induces the enzyme, differential effects on betaine and lignin biosynthesis, overview	Atriplex nummularia

Cloned(Commentary)

Cloned (Comment)	Organism
gene SAMS1, a housekeeping gene, DNA and amino acid sequence determination and analysis, expression analysis and regulation, overview, expression of soluble His-tagged isozyme SAMS1 in Escherichia coli strain M15	Atriplex nummularia
gene SAMS2, a housekeeping gene, DNA and amino acid sequence determination and analysis, expression analysis and regulation, overview	Atriplex nummularia
gene SAMS3, a housekeeping gene, DNA and amino acid sequence determination and analysis, expression analysis and regulation, overview	Atriplex nummularia
gene SAMS4, a housekeeping gene, DNA and amino acid sequence determination and analysis, expression analysis and regulation, overview	Atriplex nummularia

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	-	Atriplex nummularia

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + L-methionine + H2O	Atriplex nummularia	S-adenosyl-L-methionine is required for betaine synthesis and also for the synthesis of other compounds, especially lignin, transcript levels of the enzyme are co-regulated with those of phosphoethanolamine N-methyltransferase and choline monooxygenase to supply S-adenosyl-L-methionine for betaine synthesis in the leaves, overview, enzyme regulation pattern in plant tissues, overview	phosphate + diphosphate + S-adenosyl-L-methionine	-	?

Organism

Organism	UniProt	Comment	Textmining
Atriplex nummularia	Q6F3F0	isozyme SAMS3; a halophyte, isozyme SAMS3	-
Atriplex nummularia	Q6F3F1	isozyme SAMS4; a halophyte, isozyme SAMS4	-
Atriplex nummularia	Q6F3F3	isozyme SAMS2; a halophyte, isozyme SAMS2	-
Atriplex nummularia	Q7XZR1	isozyme SAMS1; a halophyte, isozyme SAMS1	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant His-tagged isozyme SAMS1 from Escherichia coli strain M15	Atriplex nummularia

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	-	Atriplex nummularia	-
additional information	isozyme expression pattern in plant tissues, overview	Atriplex nummularia	-
root	-	Atriplex nummularia	-
stem	-	Atriplex nummularia	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.109	-	purified recombinant His-tagged isozyme SAMS1	Atriplex nummularia

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-methionine + H2O	-	Atriplex nummularia	phosphate + diphosphate + S-adenosyl-L-methionine	-	?
ATP + L-methionine + H2O	S-adenosyl-L-methionine is required for betaine synthesis and also for the synthesis of other compounds, especially lignin, transcript levels of the enzyme are co-regulated with those of phosphoethanolamine N-methyltransferase and choline monooxygenase to supply S-adenosyl-L-methionine for betaine synthesis in the leaves, overview, enzyme regulation pattern in plant tissues, overview	Atriplex nummularia	phosphate + diphosphate + S-adenosyl-L-methionine	-	?

Synonyms

Synonyms	Comment	Organism
S-adenosyl-L-methionine synthetase	-	Atriplex nummularia
SAM synthetase	-	Atriplex nummularia
SAMS	-	Atriplex nummularia

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Atriplex nummularia

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Release 2023.1 (January 2023)