Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bacterial lipopolysaccharide | results in the accumulation of nitrites and nitrates in serum and in the inactivation of MAT I/III | Rattus norvegicus | |
carbon tetrachloride | depletion of glutathione levels reduces MAT I/III activities in vivo | Rattus norvegicus | |
Fumarylacetoacetate | reduces MAT I/III activity | Homo sapiens | |
hydrogen peroxide | reduces MAT I/III activity | Homo sapiens | |
hydrogen peroxide | - |
Rattus norvegicus | |
L-buthionine-(S,R)-sulfoximine | inactivates hepatic MAT, prevented by the administration of glutathione-ethyl ester | Rattus norvegicus | |
additional information | reactive oxygen and nitrogen species induce the inactivation of MAT I/III | Homo sapiens | |
nitric oxide | inactivates hepatic MAT | Rattus norvegicus | |
p-chloromercuribenzoate | reduces MAT I/III activity | Homo sapiens | |
S-nitrosoglutathione | inactivates MATI/III by 70% | Rattus norvegicus | |
S-nitrosoglutathione monoethyl ester | inactivates | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
tetramer | - |
Escherichia coli |
tetramer | - |
Homo sapiens |
tetramer | - |
Rattus norvegicus |