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Literature summary for 2.5.1.6 extracted from
- A comparative study of methionine adenosyltransferase activity and regional distribution in mammalian spinal cord (2000), Biochem. Pharmacol., 60, 441-445.
General Stability
| General Stability | Organism |
|---|---|
| significant decrease during the interval from 0-8 hr at 23ºC after decapitation. From here up to 72 hs post-mortem at 4ºC the activity remains at 60% of the initial value | Rattus norvegicus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0029 | - |
L-methionine | - |
Felis catus |  |
| 0.003 | - |
L-methionine | - |
Macaca mulatta | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Felis catus | - |
cat | - |
| Macaca mulatta | - |
- |
- |
| Rattus norvegicus | - |
Sprague-Dawley rats | - |
| Sus scrofa | - |
pig | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| spinal cord | - |
Rattus norvegicus | - |
| spinal cord | - |
Sus scrofa | - |
| spinal cord | - |
Bos taurus | - |
| spinal cord | - |
Felis catus | - |
| spinal cord | - |
Macaca mulatta | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-methionine + H2O | - |
Rattus norvegicus | S-adenosyl-L-methionine + phosphate + diphosphate | - |
? | |
| ATP + L-methionine + H2O | - |
Sus scrofa | S-adenosyl-L-methionine + phosphate + diphosphate | - |
? | |
| ATP + L-methionine + H2O | - |
Bos taurus | S-adenosyl-L-methionine + phosphate + diphosphate | - |
? | |
| ATP + L-methionine + H2O | - |
Felis catus | S-adenosyl-L-methionine + phosphate + diphosphate | - |
? | |
| ATP + L-methionine + H2O | - |
Macaca mulatta | S-adenosyl-L-methionine + phosphate + diphosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Rattus norvegicus |
| 37 | - |
assay at | Sus scrofa |
| 37 | - |
assay at | Bos taurus |
| 37 | - |
assay at | Felis catus |
| 37 | - |
assay at | Macaca mulatta |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.7 | - |
assay at | Sus scrofa |
| 7.7 | - |
assay at | Bos taurus |
| 7.7 | - |
assay at | Felis catus |
| 7.7 | - |
assay at | Macaca mulatta |
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Release 2023.1 (January 2023)
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