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Literature summary for 2.5.1.6 extracted from

  • Mitsui, K.i.; Teraoka, H.; Tsukada, K.
    Complete purification and immunochemical analysis of S-adenosylmethionine synthetase from bovine brain (1988), J. Biol. Chem., 263, 11211-11216.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
tripolyphosphate
-
Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
L-methionine
-
Bos taurus
0.05
-
ATP
-
Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
x * 48000 + x * 38000, SDS-PAGE Bos taurus
48000
-
x * 48000 + x * 38000, SDS-PAGE Bos taurus
160000
-
gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
bovine
-

Purification (Commentary)

Purification (Comment) Organism
partial Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
12.4
-
-
Bos taurus

Storage Stability

Storage Stability Organism
2°C, stable for at least 2 months Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxy-ATP + L-methionine + H2O
-
Bos taurus ?
-
?
3'-deoxy-ATP + L-methionine + H2O
-
Bos taurus ?
-
?
ATP + L-methionine + H2O
-
Bos taurus S-adenosyl-L-methionine + phosphate + diphosphate
-
?

Subunits

Subunits Comment Organism
? x * 48000 + x * 38000, SDS-PAGE Bos taurus