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Literature summary for 2.5.1.58 extracted from

  • Hagemann, A.; Mueller, G.; Manthey, I.; Bachmann, H.S.
    Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit (2017), FEBS Lett., 591, 3637-3648 .
    View publication on PubMed
Search for more literature for 2.5.1.58

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Rattus norvegicus
expression in Escherichia coli Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
135000
-
 PAGE, alpha subunit Homo sapiens
180000
-
 PAGE, alpha subunit Homo sapiens
225000
-
 PAGE, alpha subunit Homo sapiens
270000
-
 PAGE, alpha subunit Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P49354 and P49356 P49354 i.e. alpha-subunit, P49356 i.e. beta-subunit
-
Rattus norvegicus Q04631 AND Q02293 Q04631 i.e. alpha-subunit, Q02293 i.e. beta-subunit
-

Subunits

Subunits Comment Organism
More the alpha-subunit does not form homodimers. Crosslinking experiments reveal farnesyltransferase alpha-subunit trimers and higher oligomerization states Rattus norvegicus
More the alpha-subunit does not form homodimers. Crosslinking experiments reveal farnesyltransferase alpha-subunit trimers and higher oligomerization states Homo sapiens

Synonyms

Synonyms Comment Organism
FntA
-
 Rattus norvegicus
FntA
-
 Homo sapiens
FntB
-
 Rattus norvegicus
FntB
-
 Homo sapiens