Literature summary for 2.5.1.58 extracted from

Zhang, C.; Gao, F.; Wu, W.; Qiu, W.X.; Zhang, L.; Li, R.; Zhuang, Z.N.; Yu, W.; Cheng, H.; Zhang, X.Z.
Enzyme-driven membrane-targeted chimeric peptide for enhanced tumor photodynamic immunotherapy (2019), ACS Nano, 13, 11249-11262 .

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Application

Application	Comment	Organism
medicine	design of a protein farnesyltransferase-driven plasma membrane-targeted chimeric peptide, PpIX-C6-PEG8-KKKKKKSKTKC-OMe, for plasma membrane-targeted photodynamic therapy and enhanced immunotherapy. The plasma membrane targeting ability of the peptide originates from the cellular K-Ras signaling, which occurs exclusively to drive the corresponding proteins to plasma membrane by protein farnesyltransferase	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q61239 and Q8K2I1	Q61239 i.e. subunit alpha, Q8K2I1 i.e. subunit beta	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
4T1 cell	-	Mus musculus	-

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Release 2023.1 (January 2023)