Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.58 extracted from

  • Nguyen, U.T.; Cramer, J.; Gomis, J.; Reents, R.; Gutierrez-Rodriguez, M.; Goody, R.S.; Alexandrov, K.; Waldmann, H.
    Exploiting the substrate tolerance of farnesyltransferase for site-selective protein derivatization (2007), Chembiochem, 8, 408-423.
    View publication on PubMed
Search for more literature for 2.5.1.58

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0000684
-
 APO-GPP at room temperature Homo sapiens
0.0000886
-
 HOM-GPP at room temperature Homo sapiens
0.0003703
-
 farnesyl diphosphate at room temperature Homo sapiens
0.0003976
-
 AAA-GPP at room temperature Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AAA-GPP + N-dansyl-GCVLS
-
 Homo sapiens ?
-
 ?
APO-GPP + N-dansyl-GCVLS
-
 Homo sapiens ?
-
 ?
farnesyl diphosphate + protein-cysteine Ftase has an autonomous recognition sequence, referred to as the CAAX box, where C is a cysteine, A is usually an aliphatic amino acid, and X can be a variety of amino acids Homo sapiens diphosphate + S-farnesyl protein
-
 ?
HOM-GPP + N-dansyl-GCVLS
-
 Homo sapiens ?
-
 ?
additional information biotin-GPP is not transferred to the peptide substrate to any measurable extent Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
FTase
-
 Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.02
-
 AAA-GPP at room temperature Homo sapiens
0.042
-
 APO-GPP at room temperature Homo sapiens
0.08
-
 HOM-GPP at room temperature Homo sapiens
0.66
-
 farnesyl diphosphate at room temperature Homo sapiens