Protein Variants | Comment | Organism |
---|---|---|
Y837C | the mutant is resistant to the PFT inhibitor BMS-388891 | Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
BMS-388891 | - |
Plasmodium falciparum |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00032 | - |
farnesyl diphosphate | mutant enzyme Y837C | Plasmodium falciparum | |
0.00064 | - |
farnesyl diphosphate | wild type enzyme | Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + protein-cysteine | - |
Plasmodium falciparum | diphosphate + S-farnesyl protein | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PFT | - |
Plasmodium falciparum |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00000022 | - |
BMS-388891 | wild type enzyme | Plasmodium falciparum | |
0.0000012 | - |
BMS-388891 | mutant enzyme Y837C | Plasmodium falciparum |