Cloned (Comment) | Organism |
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- |
Pisum sativum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
manumycin | inhibition at concentration as low as 0.0025 mM, inhibitor most likely to affect only the processes that involve protein isoprenylation | Nicotiana tabacum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + protein-cysteine | Pisum sativum | potential role for plant enzyme in cell cycle regulation | S-farnesyl protein + diphosphate | - |
? | |
farnesyl diphosphate + protein-cysteine | Nicotiana tabacum | potential role for plant enzyme in cell cycle regulation | S-farnesyl protein + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Nicotiana tabacum | - |
BY-2 cells | - |
Pisum sativum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + protein-cysteine | - |
Nicotiana tabacum | diphosphate + S-farnesyl protein | - |
? | |
farnesyl diphosphate + protein-cysteine | posttranslational lipid modification in which a 15-carbon farnesyl isoprenoid is linked via a thioether bond to specific cysteine residues of proteins, the reactive cysteine is located in the C-terminal Ca1a2X motif in which C is the modified cysteine, a1 and a2 are often an aliphatic residue, and X is Ser, Met, Ala or Gln | Pisum sativum | diphosphate + S-farnesyl protein | - |
? | |
farnesyl diphosphate + protein-cysteine | prenylation, farnesylation, substrates are Ras, nuclear lamins, transducin gamma subunit, protein substrate motif: Cys-aliphatic-aliphatic-X, X: M, S, Q, A, F | Pisum sativum | diphosphate + S-farnesyl protein | - |
? | |
farnesyl diphosphate + protein-cysteine | potential role for plant enzyme in cell cycle regulation | Pisum sativum | S-farnesyl protein + diphosphate | - |
? | |
farnesyl diphosphate + protein-cysteine | potential role for plant enzyme in cell cycle regulation | Nicotiana tabacum | S-farnesyl protein + diphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | alpha-subunit of enzyme plays a role in binding isoprenyl substrates | Pisum sativum |