Application | Comment | Organism |
---|---|---|
medicine | - |
Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme inhibited by peptides containing the C-terminal CAAX sequence | Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0051 | - |
GST-CIIS | - |
Saccharomyces cerevisiae | |
0.0081 | - |
farnesyl diphosphate | - |
Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Saccharomyces cerevisiae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
1 * 43000 + 1 * 34000 | Saccharomyces cerevisiae |
43000 | - |
1 * 43000 + 1 * 34000 | Saccharomyces cerevisiae |
90000 | - |
- |
Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + GST-CIIL | - |
Saccharomyces cerevisiae | diphosphate + S-farnesyl-GST-Cys-Ile-Ile-Ser | - |
? | |
farnesyl diphosphate + GST-CIIS | GST-CIIS is glutathione S-transferase fused to the C-terminal 12 amino acids of yeast RAS2 protein | Saccharomyces cerevisiae | ? | - |
? | |
farnesyl diphosphate + protein-cysteine | prenylation, farnesylation, substrates are Ras, nuclear lamins, transducin gamma subunit, protein substrate motif: Cys-aliphatic-aliphatic-X, X: M, S, Q, A, F | Saccharomyces cerevisiae | diphosphate + S-farnesyl protein | - |
? | |
farnesyl diphosphate + [GST]-Cys-Ile-Ile-Ser | - |
Saccharomyces cerevisiae | diphosphate + S-farnesyl-[GST]-Cys-Ile-Ile-Ser | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | 1 * 43000 + 1 * 34000 | Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
- |
Saccharomyces cerevisiae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
- |
Saccharomyces cerevisiae |