BRENDA - Enzyme Database
show all sequences of 2.5.1.57

Enzymatic synthesis of sialic acid 9-phosphates

Roseman, S.; Jourdian, G.W.; Watson, D.; Rood, R.; Biochemistry 47, 958-961 (1961)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
Sus scrofa
-
N-acetyl-neuraminate 9-phosphate + phosphate
-
-
-
Organism
Organism
UniProt
Commentary
Textmining
Sus scrofa
-
pig
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Sus scrofa
Source Tissue
Source Tissue
Commentary
Organism
Textmining
submaxillary gland
-
Sus scrofa
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.2
-
-
Sus scrofa
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
637812
Sus scrofa
N-acetyl-neuraminate 9-phosphate + phosphate
-
-
-
-
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
637812
Sus scrofa
N-acetyl-neuraminate 9-phosphate + phosphate
-
637812
Sus scrofa
?
N-glycolyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
637812
Sus scrofa
N-glycolyl-neuraminate 9-phosphate + phosphate
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
Sus scrofa
-
N-acetyl-neuraminate 9-phosphate + phosphate
-
-
-
Purification (Commentary) (protein specific)
Commentary
Organism
-
Sus scrofa
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
submaxillary gland
-
Sus scrofa
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.2
-
-
Sus scrofa
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
637812
Sus scrofa
N-acetyl-neuraminate 9-phosphate + phosphate
-
-
-
-
N-acetyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
637812
Sus scrofa
N-acetyl-neuraminate 9-phosphate + phosphate
-
637812
Sus scrofa
?
N-glycolyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O
-
637812
Sus scrofa
N-glycolyl-neuraminate 9-phosphate + phosphate
-
-
-
?
Other publictions for EC 2.5.1.57
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
685801
Reaves
Replacement of the antifreeze- ...
Homo sapiens
BMB rep.
41
72-78
2008
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689622
Castilho
Construction of a functional C ...
Homo sapiens
Plant Physiol.
147
331-339
2008
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1
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671280
Gulesserian
Manifold decrease of sialic ac ...
Homo sapiens
Amino Acids
32
141-144
2007
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1
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671800
Go
Hypoxia-enhanced expression of ...
Homo sapiens
Biochem. Biophys. Res. Commun.
357
537-542
2007
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1
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671868
Hao
Elimination of 2-keto-3-deoxy- ...
Homo sapiens
Biochem. J.
397
195-201
2006
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1
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2
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5
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1
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4
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1
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2
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5
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5
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1
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2
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5
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677008
Hamada
Solution structure of the anti ...
Homo sapiens
Protein Sci.
15
1010-1016
2006
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1
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658129
Viswanathan
Engineering intracellular CMP- ...
Homo sapiens
Biochemistry
44
7526-7534
2005
-
1
-
-
-
-
-
-
-
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1
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671716
Hao
Cloning, expression, and chara ...
Homo sapiens
Biochem. Biophys. Res. Commun.
338
1507-1514
2005
-
-
1
-
-
-
8
2
-
2
2
-
-
6
-
-
1
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2
1
2
1
1
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2
1
1
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1
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8
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2
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2
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2
1
1
1
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2
1
1
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637820
Chen
Purification and characterizat ...
Escherichia coli, Homo sapiens, Rattus norvegicus
Glycobiology
12
65-71
2002
-
-
1
-
-
1
2
2
1
5
2
2
-
6
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1
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3
1
3
4
1
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1
5
2
2
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1
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3
1
3
4
1
-
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637821
Kim
Expression of a functional Dro ...
Drosophila melanogaster, Escherichia coli, Homo sapiens
Glycobiology
12
73-83
2002
-
-
2
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1
2
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8
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637819
Nakata
Molecular cloning and expressi ...
Escherichia coli, Mus musculus
Biochem. Biophys. Res. Commun.
273
642-648
2000
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2
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1
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3
2
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5
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1
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1
1
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1
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637818
Hagemeier
-
Studies on the biosynthesis of ...
Sus scrofa
Biochem. Soc. Trans.
14
1173-1174
1986
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2423
Corfield
The metabolism of sialic acids ...
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Biochem. J.
226
163-174
1985
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163
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81039
Van Rinsum
Subcellular localization and t ...
Rattus norvegicus
Biochem. J.
223
323-328
1984
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1
2
1
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2
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11
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11
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135465
Corfield
-
Changes in the activity of the ...
Rattus norvegicus, Rattus norvegicus Sprague-Dawley
Biochem. Soc. Trans.
11
766-767
1983
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163
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637813
Watson
-
N-Acylneuraminic (sialic) acid ...
Sus scrofa
Methods Enzymol.
8
201-205
1966
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1
1
2
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5
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1
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637814
Watson
The sialic acids. VIII. Sialic ...
Homo sapiens, Ovis aries, Rattus norvegicus, Sus scrofa
J. Biol. Chem.
241
5627-5636
1966
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1
1
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11
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4
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19
2
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15
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11
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1
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19
2
2
15
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1
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637812
Roseman
Enzymatic synthesis of sialic ...
Sus scrofa
Biochemistry
47
958-961
1961
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