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Literature summary for 2.5.1.46 extracted from

  • Bassani, F.; Romagnoli, A.; Cacciamani, T.; Amici, A.; Benelli, D.; Londei, P.; Maertens, B.; Blaesi, U.; La Teana, A.
    Modification of translation factor aIF5A from Sulfolobus solfataricus (2018), Extremophiles, 22, 769-780 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.46

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
144000
-
 gel filtration Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q97ZF1
-
-
Saccharolobus solfataricus DSM 1617 Q97ZF1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no synthesis of [eIF5A-precursor]-hypusine Saccharolobus solfataricus ?
-
 ?
additional information no synthesis of [eIF5A-precursor]-hypusine Saccharolobus solfataricus DSM 1617 ?
-
 ?
[eIF5A-precursor] + spermidine
-
 Saccharolobus solfataricus [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor] + spermidine
-
 Saccharolobus solfataricus DSM 1617 [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 35050, calculated from sequence, 4 * 35000, SDS-PAGE Saccharolobus solfataricus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
65
-
 assay at Saccharolobus solfataricus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9.4
-
 assay at Saccharolobus solfataricus

General Information

General Information Comment Organism
physiological function translation elongation factor aIF5A is hypusinated and also forms a stable complex with deoxyhypusine synthase Saccharolobus solfataricus