Literature summary for 2.5.1.46 extracted from

Umland, T.C.; Wolff, E.C.; Park, M.H.; Davies, D.R.
A new crystal structure of deoxyhypusine synthase reveals the configuration of the active enzyme and of an enzyme-NAD-inhibitor ternary complex (2004), J. Biol. Chem., 279, 28697-28705.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
at 2.2 A a new form II crystal of the deoxyhypusine synthase:NAD holoenzyme is grown at low ionic strength and pH 8.0, near the optimal pH for enzymatic activity	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
N1-guanyl-1,7-diaminoheptane	competitive	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P49366	recombinant enzyme	-

Synonyms

Synonyms	Comment	Organism
DHS	-	Homo sapiens

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Release 2023.1 (January 2023)