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Literature summary for 2.5.1.46 extracted from

  • Kang, K.R.; Kim, J.S.; Chang, S.II; Park, M.H.; Kim, Y.W.; Lim, D.; Lee, S.Y.
    Deoxyhypusine synthase is phosphorylated by protein kinase C in vivo as well as in vitro (2002), Exp. Mol. Med., 34, 489-495.
    View publication on PubMed
Search for more literature for 2.5.1.46

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[eIF5A-precursor]-lysine + spermidine Homo sapiens
-
 [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine Gallus gallus the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine Cricetulus griseus the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine Saccharomyces cerevisiae the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
-
-
Gallus gallus
-
-
-
Homo sapiens
-
-
-
Saccharomyces cerevisiae
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein phosphorylated by protein kinase C in vitro Gallus gallus
phosphoprotein phosphorylated by protein kinase C in vitro Cricetulus griseus
phosphoprotein phosphorylated by protein kinase C in vitro Saccharomyces cerevisiae

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[eIF5A-precursor]-lysine + spermidine
-
 Gallus gallus [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine
-
 Cricetulus griseus [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine
-
 Homo sapiens [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine
-
 Saccharomyces cerevisiae [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine
-
 Homo sapiens [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine ?
[eIF5A-precursor]-lysine + spermidine the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form Gallus gallus [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form Cricetulus griseus [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?
[eIF5A-precursor]-lysine + spermidine the enzyme catalyzes the first reaction in a two-step conversion of inactive eIF-5A to its active form Saccharomyces cerevisiae [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine
-
 ?