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Literature summary for 2.5.1.46 extracted from

  • Wolff, E.C.; Lee, Y.B.; Chung, S.I.; Folk, J.E.; Park, M.H.
    Deoxyhypusine synthase from rat testis: purification and characterization (1995), J. Biol. Chem., 270, 8660-8666.
    View publication on PubMed
Search for more literature for 2.5.1.46

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40800
-
 4 * 40800, MALDI mass spectrometry Rattus norvegicus
144000 180000 gel filtration, sedimentation equilibrium centrifugation Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
spermidine reaction in absence of eIF5A-precursor Rattus norvegicus 1,3-diaminopropane + DELTA1-pyrroline
-
 ?
[eIF5A-precursor]-lysine + spermidine
-
 Rattus norvegicus [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine ?

Subunits

Subunits Comment Organism
tetramer 4 * 40800, MALDI mass spectrometry Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
9.5 9.6
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NAD+ specific for NAD+ Rattus norvegicus