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Literature summary for 2.5.1.45 extracted from

  • Ober, D.; Hartmann, T.
    Homospermidine synthase, the first pathway-specific enzyme of pyrrolizidine alkaloid biosynthesis, evolved form deoxyhypusine synthase (1999), Proc. Natl. Acad. Sci. USA, 96, 14777-14782.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.45

Cloned(Commentary)

Cloned (Comment) Organism
-
 Senecio vernalis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40700
-
 4 * 40700, calculation from sequence of cDNA Senecio vernalis
44500
-
 4 * 44500, SDS-PAGE Senecio vernalis
174000
-
 gel filtration Senecio vernalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
putrescine + spermine Senecio vernalis
-
 sym-homospermine + propane-1,3-diamine
-
 ?

Organism

Organism UniProt Comment Textmining
Senecio vernalis Q9SC13
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Senecio vernalis

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Senecio vernalis
-
tissue culture
-
 Senecio vernalis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
putrescine + spermidine
-
 Senecio vernalis N-(4-aminobutyl)butane-1,4-diamine + propane-1,3-diamine
-
 ?
putrescine + spermine
-
 Senecio vernalis sym-homospermine + propane-1,3-diamine
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 44500, SDS-PAGE Senecio vernalis
tetramer 4 * 40700, calculation from sequence of cDNA Senecio vernalis

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Senecio vernalis
NADH
-
 Senecio vernalis