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Literature summary for 2.5.1.31 extracted from
- Undecaprenyl pyrophosphate involvement in susceptibility of Bacillus subtilis to rare earth elements (2012), J. Bacteriol., 194, 5632-5637.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| T86I | construction of strain TI392, with resistance to bacitracin, from strain YO-005, which is also modified with the mutation from strain SC26, conferring resistance to scandium, in Bacillus subtilis mutants | Bacillus subtilis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
gene uppS | - |
| Bacillus subtilis 168 | - |
gene uppS | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| undecaprenyl pyrophosphate synthase | - |
Bacillus subtilis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | naturally occurring mutation T86I confers resistance to bacitracin and scandium in Bacillus subtilis mutants | Bacillus subtilis |
| additional information | overexpression of the wild-type uppS gene results in increased susceptibilities to both scandium and bacitracin, which prevents cell wall synthesis by inhibiting the dephosphorylation of undecaprenyl diphosphate, in addition to enhanced amylase production. Accumulation of undecaprenyl diphosphate renders cells more susceptible to rare earth elements | Bacillus subtilis |
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Release 2023.1 (January 2023)
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