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Literature summary for 2.5.1.29 extracted from

  • Sagami, H.; Korenaga, T.; Ogura, K.
    Geranylgeranyl diphosphate synthase catalyzing the single condensation between isopentenyl diphosphate and farnesyl diphosphate (1993), J. Biochem., 114, 118-121.
    View publication on PubMed
Search for more literature for 2.5.1.29

Activating Compound

Activating Compound Comment Organism Structure
octyl glucoside 0.8%, 5fold activation Bos taurus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for activity Bos taurus
Mg2+ optimal activity at 5-10 mM Bos taurus
Mn2+ required for activity Bos taurus
Mn2+ optimal activity at 0.5-1 mM Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(E,E)-farnesyl diphosphate + isopentenyl diphosphate Bos taurus
-
 geranylgeranyl diphosphate + diphosphate
-
 ?
dimethylallyl diphosphate + 3 isopentenyl diphosphate Bos taurus 0.3% of the activity with farnesyl diphosphate geranylgeranyl diphosphate + 3 diphosphate
-
 ?
geranyl diphosphate + 2 isopentenyl diphosphate Bos taurus 3% of the activity with farnesyl diphosphate geranylgeranyl diphosphate + 2 diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Mono Q, isoelectric focusing, Superose 12, partial purification Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00461
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(E,E)-farnesyl diphosphate + isopentenyl diphosphate
-
 Bos taurus geranylgeranyl diphosphate + diphosphate
-
 ?
dimethylallyl diphosphate + 3 isopentenyl diphosphate 0.3% of the activity with farnesyl diphosphate Bos taurus geranylgeranyl diphosphate + 3 diphosphate
-
 ?
geranyl diphosphate + 2 isopentenyl diphosphate 3% of the activity with farnesyl diphosphate Bos taurus geranylgeranyl diphosphate + 2 diphosphate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Bos taurus