Literature summary for 2.5.1.21 extracted from

Gu, P.; Ishii, Y.; Spencer, T.A.; Shechter, I.
Function-structure studies and identification of three enzyme domains involved in the catalytic activity in rat hepatic squalene synthase (1998), J. Biol. Chem., 273, 12515-12525.

Protein Variants

Protein Variants	Comment	Organism
additional information	point mutations in conserved regions A, B, C indicate that Tyr171, Asp219, Asp223 are essential for activity and Phe288 may be involved in second step of catalysis	Rattus norvegicus

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue	Comment	Organism	Textmining

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Release 2023.1 (January 2023)