KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0095 | - |
farnesyl diphosphate | - |
Nicotiana tabacum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | integral membrane protein | Nicotiana tabacum | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
47000 | - |
x * 47000, immunoblot analysis of enzyme separated by SDS-PAGE | Nicotiana tabacum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + farnesyl diphosphate | Nicotiana tabacum | first pathway-specific enzyme in cholesterol biosynthesis | diphosphate + presqualene diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Nicotiana tabacum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Nicotiana tabacum |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell suspension culture | - |
Nicotiana tabacum | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.164 | - |
- |
Nicotiana tabacum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + farnesyl diphosphate | first pathway-specific enzyme in cholesterol biosynthesis | Nicotiana tabacum | diphosphate + presqualene diphosphate | - |
? | |
farnesyl diphosphate + NAD(P)H | - |
Nicotiana tabacum | squalene + diphosphate + NAD(P)+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 47000, immunoblot analysis of enzyme separated by SDS-PAGE | Nicotiana tabacum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
35 | - |
assay at | Nicotiana tabacum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | - |
- |
Nicotiana tabacum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | preference for NADPH over NADH | Nicotiana tabacum | |
NADPH | preference for NADPH over NADH | Nicotiana tabacum |