Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.147 extracted from

  • Philmus, B.; Decamps, L.; Berteau, O.; Begley, T.
    Biosynthetic versatility and coordinated action of 5'-deoxyadenosyl radicals in deazaflavin biosynthesis (2015), J. Am. Chem. Soc., 137, 5406-5413 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.147

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine Methanocaldococcus jannaschii the enzyme is involved in the production of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine
-
 ?
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine Methanocaldococcus jannaschii DSM 2661 the enzyme is involved in the production of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine
-
 ?

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii Q58826
-
-
Methanocaldococcus jannaschii DSM 2661 Q58826
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine
-
 Methanocaldococcus jannaschii 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine
-
 ?
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine the enzyme is involved in the production of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420 Methanocaldococcus jannaschii 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine
-
 ?
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine
-
 Methanocaldococcus jannaschii DSM 2661 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine
-
 ?
5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine the enzyme is involved in the production of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420 Methanocaldococcus jannaschii DSM 2661 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + L-methionine + 5'-deoxyadenosine
-
 ?

Synonyms

Synonyms Comment Organism
cofH
-
 Methanocaldococcus jannaschii
MjCofH
-
 Methanocaldococcus jannaschii

General Information

General Information Comment Organism
metabolism the enzyme is involved in the production of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), the precursor of the redox cofactor coenzyme F420 Methanocaldococcus jannaschii