Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.5.1.132 extracted from

  • Reaves, M.L.; Lopez, L.C.; Daskalova, S.M.
    Replacement of the antifreeze-like domain of human N-acetylneuraminic acid phosphate synthase with the mouse antifreeze-like domain impacts both N-acetylneuraminic acid 9-phosphate synthase and 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase activities (2008), BMB rep., 41, 72-78.
    View publication on PubMed
Search for more literature for 2.5.1.132

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21-AI cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information replacement of the antifreeze-like domain of human N-acetylneuraminic acid phosphate synthase with the mouse antifreeze-like domain impacts both N-acetylneuraminic acid 9-phosphate synthase and 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase activities Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + D-mannose 6-phosphate + H2O Homo sapiens
-
 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
glutathione agarose column chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + D-mannose 6-phosphate + H2O
-
 Homo sapiens 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase
-
 Homo sapiens
N-acetylneuraminic acid phosphate synthase also exhibits 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase activity Homo sapiens
NeuNAc-9-P synthase
-
 Homo sapiens