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Literature summary for 2.5.1.115 extracted from

  • Sadre, R.; Gruber, J.; Frentzen, M.
    Characterization of homogentisate prenyltransferases involved in plastoquinone-9 and tocochromanol biosynthesis (2006), FEBS Lett., 580, 5357-5362.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
n-dodecyl beta-D-maltoside stimulation at low concentration, strong inhibition above 0.1 mM Synechocystis sp.

Cloned(Commentary)

Cloned (Comment) Organism
-
Arabidopsis thaliana
-
Synechocystis sp.

Inhibitors

Inhibitors Comment Organism Structure
n-dodecyl beta-D-maltoside stimulation at low concentration, strong inhibition above 0.1 mM Synechocystis sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.001
-
(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate pH 7.5, 28°C Synechocystis sp.
0.006
-
homogentisate pH 7.5, 28°C Synechocystis sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Arabidopsis thaliana 16020
-
membrane
-
Synechocystis sp. 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ 5-10fold less stimulation than Mg2+ Synechocystis sp.
Mg2+ best activator, optimum concentration 2 mM Synechocystis sp.
Mn2+ 5-10fold less stimulation than Mg2+ Synechocystis sp.
additional information divalent cation required Synechocystis sp.

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q8VWJ1
-
-
Synechocystis sp. P73726
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranylgeranyl diphosphate + homogentisate
-
Arabidopsis thaliana diphosphate + 2-methyl-6-geranylgeranylbenzene-1,4-diol + CO2
-
?
geranylgeranyl diphosphate + homogentisate
-
Synechocystis sp. diphosphate + 2-methyl-6-geranylgeranylbenzene-1,4-diol + CO2
-
?
additional information enzyme is more active with phythyl diphosphate than with geranylgeranyl diphosphate but inactive with solanesyl diphosphate or farnesyl diphosphate Arabidopsis thaliana ?
-
?
additional information enzyme is more active with phythyl diphosphate than with geranylgeranyl diphosphate but inactive with solanesyl diphosphate or farnesyl diphosphate Synechocystis sp. ?
-
?
phytyl diphosphate + homogentisate
-
Arabidopsis thaliana diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
-
?
phytyl diphosphate + homogentisate
-
Synechocystis sp. diphosphate + 2-methyl-6-phytylbenzene-1,4-diol + CO2
-
?

Synonyms

Synonyms Comment Organism
At2g18950
-
Arabidopsis thaliana
HPT
-
Arabidopsis thaliana
HPT
-
Synechocystis sp.
slr1736 locus name Synechocystis sp.
VTE2-1
-
Arabidopsis thaliana

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Arabidopsis thaliana
7.5
-
-
Synechocystis sp.