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Literature summary for 2.5.1.106 extracted from

  • Zou, H.; Zheng, X.; Li, S.M.
    Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus (2009), J. Nat. Prod., 72, 44-52.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Aspergillus fumigatus Q4WAW7
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Aspergillus fumigatus Af293 Q4WAW7
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethylallyl diphosphate + brevianamide F
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Aspergillus fumigatus diphosphate + tryprostatin B
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?
dimethylallyl diphosphate + brevianamide F
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Aspergillus fumigatus Af293 diphosphate + tryprostatin B
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?
dimethylallyl diphosphate + DL-4-methyl-tryptophan
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Aspergillus fumigatus diphosphate + DL-1-(3'-dimethylallyl)-4-methyl-tryptophan conversion rate 7.3% ?
dimethylallyl diphosphate + DL-4-methyl-tryptophan
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Aspergillus fumigatus Af293 diphosphate + DL-1-(3'-dimethylallyl)-4-methyl-tryptophan conversion rate 7.3% ?
dimethylallyl diphosphate + DL-6-fluoro-tryptophan
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Aspergillus fumigatus diphosphate + DL-1-(3'-dimethylallyl)-6-fluoro-tryptophan conversion rate 21% ?
dimethylallyl diphosphate + DL-6-fluoro-tryptophan
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Aspergillus fumigatus Af293 diphosphate + DL-1-(3'-dimethylallyl)-6-fluoro-tryptophan conversion rate 21% ?
dimethylallyl diphosphate + DL-6-methyl-tryptophan
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Aspergillus fumigatus diphosphate + DL-1-(3'-dimethylallyl)-6-methyl-tryptophan conversion rate 36.3% ?
dimethylallyl diphosphate + DL-6-methyl-tryptophan
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Aspergillus fumigatus Af293 diphosphate + DL-1-(3'-dimethylallyl)-6-methyl-tryptophan conversion rate 36.3% ?
dimethylallyl diphosphate + DL-7-methyl-tryptophan
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Aspergillus fumigatus diphosphate + DL-1-(3'-dimethylallyl)-7-methyl-tryptophan conversion rate 24.3% ?
dimethylallyl diphosphate + L-Nalpha-methyl-tryptophan
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Aspergillus fumigatus diphosphate + L-1-(3'-dimethylallyl)-Nalpha-methyl-tryptophan conversion rate 11.1% ?
dimethylallyl diphosphate + L-tryptophan
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Aspergillus fumigatus diphosphate + L-1-(3'-dimethylallyl)-tryptophan conversion rate 37.8% ?
additional information in comparison to cyclic dipeptides, which are prenylated in a regular manner by FtmPT1 at C-2, tryptophan and its simple derivatives are prenylated reversely at N-1 Aspergillus fumigatus ?
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?
additional information in comparison to cyclic dipeptides, which are prenylated in a regular manner by FtmPT1 at C-2, tryptophan and its simple derivatives are prenylated reversely at N-1 Aspergillus fumigatus Af293 ?
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?