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Literature summary for 2.5.1.10 extracted from

  • Li, Z.H.; Cintron, R.; Koon, N.A.; Moreno, S.N.
    The N-terminus and the chain-length determination domain play a role in the length of the isoprenoid product of the bifunctional Toxoplasma gondii farnesyl diphosphate synthase (2012), Biochemistry, 51, 7533-7540.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.5.1.10

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Toxoplasma gondii

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
 x * 58000, native enzyme, SDS-PAGE Toxoplasma gondii
69600
-
 x * 69600, calculated from amino acid sequence Toxoplasma gondii
75000
-
 x * 75000, recombinant enzyme, SDS-PAGE Toxoplasma gondii

Organism

Organism UniProt Comment Textmining
Toxoplasma gondii Q197X6
-
-
Toxoplasma gondii RH Q197X6
-
-

Purification (Commentary)

Purification (Comment) Organism
anti-FLAG M2 affinity resin chromatography and nickel affinity column chromatography Toxoplasma gondii

Source Tissue

Source Tissue Comment Organism Textmining
tachyzoite
-
 Toxoplasma gondii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranyl diphosphate + isopentenyl diphosphate
-
 Toxoplasma gondii diphosphate + (2E,6E)-farnesyl diphosphate
-
 ?
geranyl diphosphate + isopentenyl diphosphate
-
 Toxoplasma gondii RH diphosphate + (2E,6E)-farnesyl diphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 75000, recombinant enzyme, SDS-PAGE Toxoplasma gondii
? x * 58000, native enzyme, SDS-PAGE Toxoplasma gondii
? x * 69600, calculated from amino acid sequence Toxoplasma gondii

Synonyms

Synonyms Comment Organism
farnesyl diphosphate synthase Toxoplasma gondii possesses a bifunctional farnesyl diphosphate/geranylgeranyl diphosphate synthase Toxoplasma gondii
FPPS
-
 Toxoplasma gondii