Protein Variants | Comment | Organism |
---|---|---|
F220A | 100000fold decrease in catalytic activity | Geobacillus stearothermophilus |
Q221E | 1000fold decrease in catalytic activity | Geobacillus stearothermophilus |
R295V | no marked change in catalytic activity | Geobacillus stearothermophilus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylallyl diphosphate + isopentenyl diphosphate | Geobacillus stearothermophilus | key enzyme in isoprenoid biosynthesis | diphosphate + geranyl diphosphate | - |
? | |
geranyl diphosphate + isopentenyl diphosphate | Geobacillus stearothermophilus | key enzyme in isoprenoid biosynthesis | diphosphate + trans,trans-farnesyl diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacillus stearothermophilus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylallyl diphosphate + isopentenyl diphosphate | key enzyme in isoprenoid biosynthesis | Geobacillus stearothermophilus | diphosphate + geranyl diphosphate | - |
? | |
dimethylallyl diphosphate + isopentenyl diphosphate | the synthase amino-acid residues at the 4th and 5th position before the first aspartate rich motif mainly determine product specificity | Geobacillus stearothermophilus | diphosphate + geranyl diphosphate | - |
? | |
geranyl diphosphate + isopentenyl diphosphate | key enzyme in isoprenoid biosynthesis | Geobacillus stearothermophilus | diphosphate + trans,trans-farnesyl diphosphate | - |
? | |
geranyl diphosphate + isopentenyl diphosphate | the synthase amino-acid residues at the 4th and 5th position before the first aspartate rich motif mainly determine product specificity | Geobacillus stearothermophilus | diphosphate + trans,trans-farnesyl diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
farnesyl diphosphate synthase | - |
Geobacillus stearothermophilus |
FPPS | - |
Geobacillus stearothermophilus |