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Literature summary for 2.4.2.9 extracted from
- UMP pyrophosphorylase of Tetrahymena pyriformis. Partial purification and properties (1978), Arch. Biochem. Biophys., 187, 264-271.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition by cytosine, orotic acid, 6-azauracil | Tetrahymena pyriformis | |
| UTP | - |
Tetrahymena pyriformis |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0004 | - |
Uracil | - |
Tetrahymena pyriformis | |
| 0.0069 | - |
5-phospho-alpha-D-ribose 1-diphosphate | - |
Tetrahymena pyriformis | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 36000 | - |
- |
Tetrahymena pyriformis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tetrahymena pyriformis | - |
- |
- |
| Tetrahymena pyriformis GL-7 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Tetrahymena pyriformis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 6-azauracil + 5-phospho-alpha-D-ribose 1-diphosphate | no activity | Tetrahymena pyriformis | 6-aza-UMP + diphosphate | - |
? | |
| 6-azauracil + 5-phospho-alpha-D-ribose 1-diphosphate | no activity | Tetrahymena pyriformis GL-7 | 6-aza-UMP + diphosphate | - |
? | |
| additional information | no substrates: cytosine, orotic acid | Tetrahymena pyriformis | ? | - |
? | |
| additional information | no substrates: cytosine, orotic acid | Tetrahymena pyriformis GL-7 | ? | - |
? | |
| uracil + 5-phospho-alpha-D-ribose 1-diphosphate | highly specific for uracil | Tetrahymena pyriformis | UMP + diphosphate | - |
? | |
| uracil + 5-phospho-alpha-D-ribose 1-diphosphate | highly specific for uracil | Tetrahymena pyriformis GL-7 | UMP + diphosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Tetrahymena pyriformis |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
irreversible inactivation above | Tetrahymena pyriformis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | 8 | - |
Tetrahymena pyriformis |
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