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Literature summary for 2.4.2.8 extracted from

  • Zheng, K.C.; Yalowich, J.C.; Kagan, V.E.; Keohavong, P.
    Increased mutant frequencies in the HPRT gene locus of leukemia HL-60 cells treated with succinylacetone (2006), Cell Biol. Toxicol., 22, 361-370.
    View publication on PubMed

Application

Application Comment Organism
molecular biology the HPRT gene is used as reporter gene in HL-60 cells for investigation of the mutagenic potential of succinyl-acetone by determining the frequencies of somatic mutations in the HPRT reporter gene, overview Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
gene HPRT, determination of the mutagenic potential of succinyl-acetone by determining the frequencies of somatic mutations in the HPRT reporter gene, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HL-60 cell myeloid leukemic cell line Homo sapiens
-

Synonyms

Synonyms Comment Organism
HPRT
-
Homo sapiens
hypoxanthine-guanine phosphoribosyl transferase
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Homo sapiens